Novel Gastroretentive Floating Pulsatile Drug Delivery System Produced via Hot-Melt Extrusion and Fused Deposition Modeling 3D Printing

Novel Gastroretentive Floating Pulsatile Drug Delivery System Produced via Hot-Melt Extrusion and Fused Deposition Modeling 3D Printing

This study was performed to develop novel core-shell gastroretentive floating pulsatile drug delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D printing and direct compression method. Hydroxypropyl cellulose (HPC) and ethyl cellulose (EC)-based filaments were fabri...

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Bibliographic Details
Main Authors: Nagi Reddy Dumpa, Suresh Bandari, Michael A. Repka
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
hot-melt extrusion
fused deposition modeling
3d printing
floating systems
pulsatile release
chronotherapeutic delivery
Online Access:https://www.mdpi.com/1999-4923/12/1/52

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