Myocardial tissue characterisation using echocardiographic deformation imaging
Abstract Myocardial pathology results in significant morbidity and mortality, whether due to primary cardiomyopathic processes or secondary to other conditions such as ischemic heart disease. Cardiac imaging techniques characterise the underlying tissue directly, by assessing a signal from the tissu...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
|
Series: | Cardiovascular Ultrasound |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12947-019-0176-9 |
id |
doaj-b8bc837e1d07480794d972b09ca9b6fa |
---|---|
record_format |
Article |
spelling |
doaj-b8bc837e1d07480794d972b09ca9b6fa2020-11-25T04:07:19ZengBMCCardiovascular Ultrasound1476-71202019-11-0117111110.1186/s12947-019-0176-9Myocardial tissue characterisation using echocardiographic deformation imagingMohammed A. Moharram0Regis R. Lamberts1Gillian Whalley2Michael J. A. Williams3Sean Coffey4Department of Medicine – HeartOtago, Dunedin School of Medicine, University of OtagoDepartment of Physiology – HeartOtago, School of Biomedical Sciences, University of OtagoDepartment of Medicine – HeartOtago, Dunedin School of Medicine, University of OtagoDepartment of Medicine – HeartOtago, Dunedin School of Medicine, University of OtagoDepartment of Medicine – HeartOtago, Dunedin School of Medicine, University of OtagoAbstract Myocardial pathology results in significant morbidity and mortality, whether due to primary cardiomyopathic processes or secondary to other conditions such as ischemic heart disease. Cardiac imaging techniques characterise the underlying tissue directly, by assessing a signal from the tissue itself, or indirectly, by inferring tissue characteristics from global or regional function. Cardiac magnetic resonance imaging is currently the most investigated imaging modality for tissue characterisation, but, due to its accessibility, advanced echocardiography represents an attractive alternative. Speckle tracking echocardiography (STE) is a reproducible technique used to assess myocardial deformation at both segmental and global levels. Since distinct myocardial pathologies affect deformation differently, information about the underlying tissue can be inferred by STE. In this review, the current available studies correlating STE deformation parameters with underlying tissue characteristics in humans are examined, with separate emphasis on global and segmental analysis. The current knowledge is placed in the context of integrated backscatter and the future of echocardiographic based tissue characterisation is discussed. The use of these imaging techniques to more precisely phenotype myocardial pathology more precisely will allow the design of translational cardiac research studies and, potentially, tailored management strategies.http://link.springer.com/article/10.1186/s12947-019-0176-9EchocardiographyStrainSpeckle trackingFibrosisMyocardial histology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammed A. Moharram Regis R. Lamberts Gillian Whalley Michael J. A. Williams Sean Coffey |
spellingShingle |
Mohammed A. Moharram Regis R. Lamberts Gillian Whalley Michael J. A. Williams Sean Coffey Myocardial tissue characterisation using echocardiographic deformation imaging Cardiovascular Ultrasound Echocardiography Strain Speckle tracking Fibrosis Myocardial histology |
author_facet |
Mohammed A. Moharram Regis R. Lamberts Gillian Whalley Michael J. A. Williams Sean Coffey |
author_sort |
Mohammed A. Moharram |
title |
Myocardial tissue characterisation using echocardiographic deformation imaging |
title_short |
Myocardial tissue characterisation using echocardiographic deformation imaging |
title_full |
Myocardial tissue characterisation using echocardiographic deformation imaging |
title_fullStr |
Myocardial tissue characterisation using echocardiographic deformation imaging |
title_full_unstemmed |
Myocardial tissue characterisation using echocardiographic deformation imaging |
title_sort |
myocardial tissue characterisation using echocardiographic deformation imaging |
publisher |
BMC |
series |
Cardiovascular Ultrasound |
issn |
1476-7120 |
publishDate |
2019-11-01 |
description |
Abstract Myocardial pathology results in significant morbidity and mortality, whether due to primary cardiomyopathic processes or secondary to other conditions such as ischemic heart disease. Cardiac imaging techniques characterise the underlying tissue directly, by assessing a signal from the tissue itself, or indirectly, by inferring tissue characteristics from global or regional function. Cardiac magnetic resonance imaging is currently the most investigated imaging modality for tissue characterisation, but, due to its accessibility, advanced echocardiography represents an attractive alternative. Speckle tracking echocardiography (STE) is a reproducible technique used to assess myocardial deformation at both segmental and global levels. Since distinct myocardial pathologies affect deformation differently, information about the underlying tissue can be inferred by STE. In this review, the current available studies correlating STE deformation parameters with underlying tissue characteristics in humans are examined, with separate emphasis on global and segmental analysis. The current knowledge is placed in the context of integrated backscatter and the future of echocardiographic based tissue characterisation is discussed. The use of these imaging techniques to more precisely phenotype myocardial pathology more precisely will allow the design of translational cardiac research studies and, potentially, tailored management strategies. |
topic |
Echocardiography Strain Speckle tracking Fibrosis Myocardial histology |
url |
http://link.springer.com/article/10.1186/s12947-019-0176-9 |
work_keys_str_mv |
AT mohammedamoharram myocardialtissuecharacterisationusingechocardiographicdeformationimaging AT regisrlamberts myocardialtissuecharacterisationusingechocardiographicdeformationimaging AT gillianwhalley myocardialtissuecharacterisationusingechocardiographicdeformationimaging AT michaeljawilliams myocardialtissuecharacterisationusingechocardiographicdeformationimaging AT seancoffey myocardialtissuecharacterisationusingechocardiographicdeformationimaging |
_version_ |
1724429265389223936 |