Imatinib and hypophosphatemia: Case report and review of literature

Imatinib mesylate is a potent inhibitor of the BCR-Abl kinases, c-Kit, PDGFR, and fms. Imatinib used for treatment of chronic myeloid leukemia and gastrointestinal stromal tumor. Imatinib has been well tolerated. The most common adverse events reported included edema, nausea, diarrhea, myalgia or mu...

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Main Authors: Erdem Şen, İrem Öner, Özlem Ata
Format: Article
Language:English
Published: Turkiye Klinikleri 2017-07-01
Series:Journal of Oncological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452336417300031
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spelling doaj-b8bebdaee9f94a4884c246843f7995d42020-11-25T01:49:11ZengTurkiye KlinikleriJournal of Oncological Sciences2452-33642017-07-0132929510.1016/j.jons.2017.05.002Imatinib and hypophosphatemia: Case report and review of literatureErdem Şenİrem ÖnerÖzlem AtaImatinib mesylate is a potent inhibitor of the BCR-Abl kinases, c-Kit, PDGFR, and fms. Imatinib used for treatment of chronic myeloid leukemia and gastrointestinal stromal tumor. Imatinib has been well tolerated. The most common adverse events reported included edema, nausea, diarrhea, myalgia or musculoskeletal pain, fatigue, dermatitis or rash, headache and abdominal pain. Hypophosphatemia is rare side effect of imatinib treatment. This is the report of a case experiencing severe hypophosphatemia during adjuvant treatment with imatinib for gastrointestinal stromal tumor.http://www.sciencedirect.com/science/article/pii/S2452336417300031ImatinibHypophosphatemiaGastrointestinal stromal tumor
collection DOAJ
language English
format Article
sources DOAJ
author Erdem Şen
İrem Öner
Özlem Ata
spellingShingle Erdem Şen
İrem Öner
Özlem Ata
Imatinib and hypophosphatemia: Case report and review of literature
Journal of Oncological Sciences
Imatinib
Hypophosphatemia
Gastrointestinal stromal tumor
author_facet Erdem Şen
İrem Öner
Özlem Ata
author_sort Erdem Şen
title Imatinib and hypophosphatemia: Case report and review of literature
title_short Imatinib and hypophosphatemia: Case report and review of literature
title_full Imatinib and hypophosphatemia: Case report and review of literature
title_fullStr Imatinib and hypophosphatemia: Case report and review of literature
title_full_unstemmed Imatinib and hypophosphatemia: Case report and review of literature
title_sort imatinib and hypophosphatemia: case report and review of literature
publisher Turkiye Klinikleri
series Journal of Oncological Sciences
issn 2452-3364
publishDate 2017-07-01
description Imatinib mesylate is a potent inhibitor of the BCR-Abl kinases, c-Kit, PDGFR, and fms. Imatinib used for treatment of chronic myeloid leukemia and gastrointestinal stromal tumor. Imatinib has been well tolerated. The most common adverse events reported included edema, nausea, diarrhea, myalgia or musculoskeletal pain, fatigue, dermatitis or rash, headache and abdominal pain. Hypophosphatemia is rare side effect of imatinib treatment. This is the report of a case experiencing severe hypophosphatemia during adjuvant treatment with imatinib for gastrointestinal stromal tumor.
topic Imatinib
Hypophosphatemia
Gastrointestinal stromal tumor
url http://www.sciencedirect.com/science/article/pii/S2452336417300031
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