Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse
<p>Abstract</p> <p>Background</p> <p>Mitral valve thickness is used as a criterion to distinguish the classical from the non-classical form of mitral valve prolapse (MVP). Classical form of MVP has been associated with higher risk of mitral regurgitation (MR) and concom...
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doaj-b8ceb26c1e8c43ecb18549835869dd122020-11-25T00:16:50ZengBMCCardiovascular Ultrasound1476-71202012-01-01101310.1186/1476-7120-10-3Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapseSénéchal MarioMichaud NicolasMacHaalany JimmyBernier MathieuDubois MichelleMagne JulienCouture ChristianMathieu PatrickBertrand Olivier FVoisine Pierre<p>Abstract</p> <p>Background</p> <p>Mitral valve thickness is used as a criterion to distinguish the classical from the non-classical form of mitral valve prolapse (MVP). Classical form of MVP has been associated with higher risk of mitral regurgitation (MR) and concomitant complications. We sought to determine the relation of mitral valve morphology and motion to mitral regurgitation severity in patients with MVP.</p> <p>Methods</p> <p>We prospectively analyzed transthoracic echocardiograms of 38 consecutive patients with MVP and various degrees of MR. In the parasternal long-axis view, leaflets length, diastolic leaflet thickness, prolapsing depth, billowing area and non-coaptation distance between both leaflets were measured.</p> <p>Results</p> <p>Twenty patients (53%) and 18 patients (47%) were identified as having moderate to severe and mild MR respectively (ERO = 45 ± 27 mm<sup>2 </sup>vs. 5 ± 7 mm<sup>2</sup>, p < 0.001). Diastolic leaflet thickness was similar in both groups (5.5 ± 0.9 mm vs. 5.3 ± 1 mm, p = 0.57). On multivariate analysis, the non-coaptation distance (OR 7.9 per 1 mm increase; 95% CI 1.72-37.2) was associated with significant MR. Thick mitral valve leaflet as traditionally reported (≥ 5 mm) was not associated with significant MR (OR 0.9; 95% CI 0.2-3.4).</p> <p>Conclusions</p> <p>In patients with MVP, thick mitral leaflet is not associated with significant MR. Leaflet thickness is probably not as important in risk stratification as previously reported in patients with MVP. Other anatomical and geometrical features of the mitral valve apparatus area appear to be much more closely related to MR severity.</p> http://www.cardiovascularultrasound.com/content/10/1/3mitral regurgitationmitral valveechocardiographymitral valve prolapse |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sénéchal Mario Michaud Nicolas MacHaalany Jimmy Bernier Mathieu Dubois Michelle Magne Julien Couture Christian Mathieu Patrick Bertrand Olivier F Voisine Pierre |
spellingShingle |
Sénéchal Mario Michaud Nicolas MacHaalany Jimmy Bernier Mathieu Dubois Michelle Magne Julien Couture Christian Mathieu Patrick Bertrand Olivier F Voisine Pierre Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse Cardiovascular Ultrasound mitral regurgitation mitral valve echocardiography mitral valve prolapse |
author_facet |
Sénéchal Mario Michaud Nicolas MacHaalany Jimmy Bernier Mathieu Dubois Michelle Magne Julien Couture Christian Mathieu Patrick Bertrand Olivier F Voisine Pierre |
author_sort |
Sénéchal Mario |
title |
Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
title_short |
Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
title_full |
Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
title_fullStr |
Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
title_full_unstemmed |
Relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
title_sort |
relation of mitral valve morphology and motion to mitral regurgitation severity in patients with mitral valve prolapse |
publisher |
BMC |
series |
Cardiovascular Ultrasound |
issn |
1476-7120 |
publishDate |
2012-01-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Mitral valve thickness is used as a criterion to distinguish the classical from the non-classical form of mitral valve prolapse (MVP). Classical form of MVP has been associated with higher risk of mitral regurgitation (MR) and concomitant complications. We sought to determine the relation of mitral valve morphology and motion to mitral regurgitation severity in patients with MVP.</p> <p>Methods</p> <p>We prospectively analyzed transthoracic echocardiograms of 38 consecutive patients with MVP and various degrees of MR. In the parasternal long-axis view, leaflets length, diastolic leaflet thickness, prolapsing depth, billowing area and non-coaptation distance between both leaflets were measured.</p> <p>Results</p> <p>Twenty patients (53%) and 18 patients (47%) were identified as having moderate to severe and mild MR respectively (ERO = 45 ± 27 mm<sup>2 </sup>vs. 5 ± 7 mm<sup>2</sup>, p < 0.001). Diastolic leaflet thickness was similar in both groups (5.5 ± 0.9 mm vs. 5.3 ± 1 mm, p = 0.57). On multivariate analysis, the non-coaptation distance (OR 7.9 per 1 mm increase; 95% CI 1.72-37.2) was associated with significant MR. Thick mitral valve leaflet as traditionally reported (≥ 5 mm) was not associated with significant MR (OR 0.9; 95% CI 0.2-3.4).</p> <p>Conclusions</p> <p>In patients with MVP, thick mitral leaflet is not associated with significant MR. Leaflet thickness is probably not as important in risk stratification as previously reported in patients with MVP. Other anatomical and geometrical features of the mitral valve apparatus area appear to be much more closely related to MR severity.</p> |
topic |
mitral regurgitation mitral valve echocardiography mitral valve prolapse |
url |
http://www.cardiovascularultrasound.com/content/10/1/3 |
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