Rodent 2-year cancer bioassays and in vitro and in vivo genotoxicity tests insufficiently predict risk or model development of human carcinomas
In 2018, the National Institutes of Health estimated that 1,735,350 new cancer cases were diagnosed in the United States and 609,640 patients died from various forms of cancer. The vast majority of those cancer deaths occurred from cancers derived from epithelial cells, that is, carcinomas. The most...
Main Authors: | Carr J Smith, Thomas A Perfetti, Judy A King |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-05-01
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Series: | Toxicology Research and Application |
Online Access: | https://doi.org/10.1177/2397847319849648 |
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