Physicochemical Interactions in Nanofunctionalized Alginate/GelMA IPN Hydrogels

• Main Authors: Rana Kadri, Kamil Elkhoury, Ghazi Ben Messaoud, Cyril Kahn, Ali Tamayol, Joao F. Mano, Elmira Arab-Tehrany, Laura Sánchez-González
• Format: Article
• Language: English
• Published: MDPI AG 2021-08-01
• Series: Nanomaterials
• Subjects: alginate; gelatin; IPN hydrogels; functionalization; nanoliposomes; biomimetic nanocomposites
• Online Access: https://www.mdpi.com/2079-4991/11/9/2256

Polymeric hydrogels are currently at the center of research due to their particular characteristics. They have tunable physical, chemical, and biological properties making them a material of choice for a large range of applications. Polymer-composite and nanocomposite hydrogels were developed to enhance the native hydrogel’s properties and to include numerous functionalities. In this work, alginate/gelatin-methacryloyl-based interpenetrating polymer network hydrogels were prepared with different alginate concentrations and investigated before and after the functionalization with nanoliposomes. The multiscale analysis was obtained through Fourier transform infrared spectroscopy and proton nuclear magnetic resonance. The results show interactions between two polymers as well as between the nanoliposomes and biopolymer.