Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix

• Main Authors: Wuntkal Rekha, Shet Tanuja, Gupta Sudeep, Maheshwari Amita, Tongaonkar Hemant B
• Format: Article
• Language: English
• Published: BMC 2006-07-01
• Series: World Journal of Surgical Oncology
• Online Access: http://www.wjso.com/content/4/1/36

<p>Abstract</p> <p>Background</p> <p>Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare.</p> <p>Case presentation</p> <p>We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy.</p> <p>Conclusion</p> <p>Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient.</p>