Summary: | The electromagnetic frequencies that induced normally in human body, comprise from the action potentials of nerves, heart tissue and skeletal muscles, were categorized in the range of extremely low frequencies. With increase in developed devices that produced or induced electromagnetic fields, human anxiety about effects of these fields on normal or abnormal body cell proliferation was increased. Experiments provided on cells and tissues indicated that electromagnetic fields at different strengths and frequencies had altered effects on cell proliferation and differentiation. Thus, this systematic review analyzed different findings and focused on extremely low frequency electromagnetic field effects on cell proliferation. The observations reinforced pulsed extremely low frequency electromagnetic fields in frequencies between 15-60 Hz had more effects on cell proliferation and less effect on cell differentiation. This effect was related to multi- session irradiation or cells long term exposure. Extremely low frequency electromagnetic fields can use as a safe stimulator for cell proliferation and repair of tissue damages
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