Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors

Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors

Abstract Background While cure rates for childhood acute lymphoblastic leukemia (cALL) now exceed 80%, over 60% of survivors will face treatment-related long-term sequelae, including cardiometabolic complications such as obesity, insulin resistance, dyslipidemia and hypertension. Although genetic su...

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Bibliographic Details
Main Authors: Jade England, Simon Drouin, Patrick Beaulieu, Pascal St-Onge, Maja Krajinovic, Caroline Laverdière, Emile Levy, Valérie Marcil, Daniel Sinnett
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Acute lymphoblastic leukemia
cancer survivors
genetic determinants
cardiometabolic complications
genetic association study
extreme phenotype
Online Access:http://link.springer.com/article/10.1186/s12885-017-3722-6

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