The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism
Characteristics of parathyroid glands usually determined by ultrasonography such as its total weight or volume might be a good indicator for the induction or suppression of parathyroid hormone (PTH) secretion from these glands. In the present study, we investigated the relationship between the volum...
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Wolters Kluwer Medknow Publications
2016-01-01
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Series: | Saudi Journal of Kidney Diseases and Transplantation |
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doaj-b90a8c7dfb1c486ca2ffef0201efda522020-11-25T01:19:19ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422016-01-0127226326910.4103/1319-2442.178257The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidismFarrokhlagha AhmadiPegah AghajanzadehHadi Rokni YazdiSima MaziarSayad Mansour GatmiriCharacteristics of parathyroid glands usually determined by ultrasonography such as its total weight or volume might be a good indicator for the induction or suppression of parathyroid hormone (PTH) secretion from these glands. In the present study, we investigated the relationship between the volume and blood supply grade of the parathyroid glands, and its PTH secretion. Study subjects included 52 consecutive patients with the secondary hyperparathyroidism undergoing maintenance hemodialysis therapy referred to dialysis wards of the Imam Khomeini and Amiralam University Hospitals in Tehran. Serum intact PTH (i-PTH) was measured by an ELISA assay. The parathyroid glands characteristics were identified by ultrasonography that was performed simultaneously with blood collection. Parathyroid blood flows were evaluated by power-Doppler color imaging. There was no significant correlation between the total mass of the glands and serum concentration of i-PTH. No significant correlations were also observed between both total central and peripheral parathyroid glands blood flow and serum i-PTH level. Dialysis duration and serum alkaline phosphatase were significantly correlated in a positive manner with i-PTH level. Furthermore, serum level of i-PTH was not correlated with the total signals of glands blood flow in a multivariable linear regression analysis. Serum secreted i-PTH level might not be predictable by a total mass of parathyroid glands as well as their blood supply.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=263;epage=269;aulast=Ahmadi |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Farrokhlagha Ahmadi Pegah Aghajanzadeh Hadi Rokni Yazdi Sima Maziar Sayad Mansour Gatmiri |
spellingShingle |
Farrokhlagha Ahmadi Pegah Aghajanzadeh Hadi Rokni Yazdi Sima Maziar Sayad Mansour Gatmiri The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism Saudi Journal of Kidney Diseases and Transplantation |
author_facet |
Farrokhlagha Ahmadi Pegah Aghajanzadeh Hadi Rokni Yazdi Sima Maziar Sayad Mansour Gatmiri |
author_sort |
Farrokhlagha Ahmadi |
title |
The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
title_short |
The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
title_full |
The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
title_fullStr |
The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
title_full_unstemmed |
The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
title_sort |
relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism |
publisher |
Wolters Kluwer Medknow Publications |
series |
Saudi Journal of Kidney Diseases and Transplantation |
issn |
1319-2442 |
publishDate |
2016-01-01 |
description |
Characteristics of parathyroid glands usually determined by ultrasonography such as its total weight or volume might be a good indicator for the induction or suppression of parathyroid hormone (PTH) secretion from these glands. In the present study, we investigated the relationship between the volume and blood supply grade of the parathyroid glands, and its PTH secretion. Study subjects included 52 consecutive patients with the secondary hyperparathyroidism undergoing maintenance hemodialysis therapy referred to dialysis wards of the Imam Khomeini and Amiralam University Hospitals in Tehran. Serum intact PTH (i-PTH) was measured by an ELISA assay. The parathyroid glands characteristics were identified by ultrasonography that was performed simultaneously with blood collection. Parathyroid blood flows were evaluated by power-Doppler color imaging. There was no significant correlation between the total mass of the glands and serum concentration of i-PTH. No significant correlations were also observed between both total central and peripheral parathyroid glands blood flow and serum i-PTH level. Dialysis duration and serum alkaline phosphatase were significantly correlated in a positive manner with i-PTH level. Furthermore, serum level of i-PTH was not correlated with the total signals of glands blood flow in a multivariable linear regression analysis. Serum secreted i-PTH level might not be predictable by a total mass of parathyroid glands as well as their blood supply. |
url |
http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=263;epage=269;aulast=Ahmadi |
work_keys_str_mv |
AT farrokhlaghaahmadi therelationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT pegahaghajanzadeh therelationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT hadirokniyazdi therelationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT simamaziar therelationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT sayadmansourgatmiri therelationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT farrokhlaghaahmadi relationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT pegahaghajanzadeh relationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT hadirokniyazdi relationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT simamaziar relationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism AT sayadmansourgatmiri relationshipbetweentotalmassandbloodsupplyofparathyroidglandsandtheirsecretionofparathyroidhormoneinhemodialysispatientswithsecondaryhyperparathyroidism |
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1725138941497049088 |