Inhibitory Effects of Diketopiperazines from Marine-Derived <i>Streptomyces puniceus</i> on the Isocitrate Lyase of <i>Candida albicans</i>
The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase, and plays an important role in the pathogenesis of microorganisms during infection. An <i>icl</i>-deletion mutant of <i>Candida albicans</i> ex...
Main Authors: | Heegyu Kim, Ji-Yeon Hwang, Jongheon Shin, Ki-Bong Oh |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/24/11/2111 |
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