Extrajunctional resting Ca2+ influx is not increased in a severely dystrophic expiratory muscle (triangularis sterni) of the mdx mouse

Extrajunctional resting Ca2+ influx is not increased in a severely dystrophic expiratory muscle (triangularis sterni) of the mdx mouse

Freshly isolated adult mdx and nondystrophic (C57B110SnJ) muscle fibers were used to examine the potential role of resting Ca2+ influx in the pathogenesis of Duchenne and related dystrophies. Microfluorimetric determinations of resting divalent cation influx were obtained from undissociated intact m...

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Bibliographic Details
Main Authors: C.George Carlson, Anton Gueorguiev, Diana M Roshek, Rebecca Ashmore, Jacquelyne S Chu, Judy E Anderson
Format: Article
Language:English
Published: Elsevier 2003-11-01
Series:Neurobiology of Disease
Subjects:
Duchenne muscular dystrophy
mdx mouse
Dystrophinopathies
Calcium
Calcium channels
Muscle necrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001281

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http://www.sciencedirect.com/science/article/pii/S0969996103001281

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