Differential methylation and expression patterns of microRNAs in relation to breast cancer subtypes among American women of African and European ancestry.

Differential methylation and expression patterns of microRNAs in relation to breast cancer subtypes among American women of African and European ancestry.

Aggressive high-grade, estrogen receptor negative (ER-) breast cancer is more common among American women of African ancestry (AA) than those of European ancestry (EA). Epigenetic mechanisms, particularly DNA methylation and altered microRNA (miRNA) expression, may contribute to racial differences i...

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Bibliographic Details
Main Authors: Zhihong Gong, Jianhong Chen, Jie Wang, Song Liu, Christine B Ambrosone, Michael J Higgins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0249229

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