Live Attenuated Salmonella enterica Expressing and Releasing Cell-Permeable Bax BH3 Peptide Through the MisL Autotransporter System Elicits Antitumor Activity in a Murine Xenograft Model of Human B Non-hodgkin's Lymphoma

Live Attenuated Salmonella enterica Expressing and Releasing Cell-Permeable Bax BH3 Peptide Through the MisL Autotransporter System Elicits Antitumor Activity in a Murine Xenograft Model of Human B Non-hodgkin's Lymphoma

The survival of patients with non-Hodgkin's lymphoma (NHL) has substantially improved with current treatments. Nevertheless, the appearance of drug-resistant cancer cells leads to patient relapse. It is therefore necessary to find new antitumor therapies that can completely eradicate transforme...

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Bibliographic Details
Main Authors: Armando Alfredo Mateos-Chávez, Paola Muñoz-López, Elayne Irene Becerra-Báez, Luis Fernando Flores-Martínez, Diego Prada-Gracia, Liliana Marisol Moreno-Vargas, Guillermina Juliana Baay-Guzmán, Uriel Juárez-Hernández, Bibiana Chávez-Munguía, Lourdes Cabrera-Muñóz, Rosendo Luria-Pérez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
non-Hodgkin's lymphoma
Salmonella enterica
cancer
Bax BH3 peptide
apoptosis
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02562/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02562/full

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