Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico.

<h4>Background</h4>The progressive disseminated histoplasmosis (PDH) has been associated with severe disease and high risk of death among people living with HIV (PLWHIV). Therefore, the purpose of this multicenter, prospective, double-blinded study done in ten Mexican hospitals was to de...

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Main Authors: Areli Martínez-Gamboa, María Dolores Niembro-Ortega, Pedro Torres-González, Janeth Santiago-Cruz, Nancy Guadalupe Velázquez-Zavala, Andrea Rangel-Cordero, Brenda Crabtree-Ramírez, Armando Gamboa-Domínguez, Edgardo Reyes-Gutiérrez, Gustavo Reyes-Terán, Víctor Hugo Lozano-Fernandez, Víctor Hugo Ahumada-Topete, Pedro Martínez-Ayala, Marisol Manríquez-Reyes, Juan Pablo Ramírez-Hinojosa, Patricia Rodríguez-Zulueta, Christian Hernández-León, Jesús Ruíz-Quiñones, Norma Eréndira Rivera-Martínez, Alberto Chaparro-Sánchez, Jaime Andrade-Villanueva, Luz Alicia González-Hernández, Sofia Cruz-Martínez, Oscar Flores-Barrientos, Jesús Enrique Gaytán-Martínez, Martín Magaña-Aquino, Axel Cervantes-Sánchez, Antonio Olivas-Martínez, Javier Araujo-Meléndez, María Del Rocío Reyes-Montes, Esperanza Duarte-Escalante, María Guadalupe Frías-De León, José Antonio Ramírez, María Lucia Taylor, Alfredo Ponce de León-Garduño, José Sifuentes-Osornio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009215