Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis

Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis

Abstract Background The signal transducer and activator of transcription 6 (STAT6) transcription factor plays a vitally important role in immune cells, where it is activated mainly by interleukin-4 (IL-4). Because IL-4 is an essential cytokine for myotube formation, STAT6 might also be involved in m...

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Bibliographic Details
Main Authors: Mitsutoshi Kurosaka, Yuji Ogura, Shuichi Sato, Kazuhisa Kohda, Toshiya Funabashi
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Skeletal Muscle
Subjects:
Myotube
Myoblast fusion
Differentiation
Primary myoblast
Interleukin-4
Online Access:https://doi.org/10.1186/s13395-021-00271-8

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