Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature
Systemic sarcoidosis is a disease of unknown etiology, with the liver being the third most commonly affected organ. Most cases of hepatic sarcoidosis are not clinically apparent, but a few can progress to liver cirrhosis, portal hypertension and ultimately liver failure. The diagnosis of hepatic sar...
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doaj-b97c18d6113c4bf4b09f2ec29edbd2662020-11-24T20:41:36ZengKarger PublishersCase Reports in Gastroenterology1662-06312012-04-016118318910.1159/000338355338355Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the LiteratureChristopher B. TanSadat RashidDhyan RajanWondwoosen GebrePaul MustacchiaSystemic sarcoidosis is a disease of unknown etiology, with the liver being the third most commonly affected organ. Most cases of hepatic sarcoidosis are not clinically apparent, but a few can progress to liver cirrhosis, portal hypertension and ultimately liver failure. The diagnosis of hepatic sarcoidosis is difficult, considering that no single laboratory test or radiographic finding can definitively diagnose this systemic disease. Diagnosis of hepatic sarcoidosis relies heavily on histopathologic evaluation of two or more organs, a diagnostic modality that is invasive and may not be applicable to all patients. The treatment of hepatic sarcoidosis is challenging, with no large randomized controlled trials done to date. Physicians must be aware of the complications of hepatic sarcoidosis, and must include the same in the differential diagnosis of liver cirrhosis. We present a case of hepatic sarcoidosis complicated by portal hypertension and liver cirrhosis.http://www.karger.com/Article/FullText/338355Portal hypertensionGastrointestinal sarcoidosisExtrapulmonary sarcoidosisHepatic sarcoidosis and liver cirrhosisHepatic sarcoidosis and portal hypertensionHepatic sarcoidosisLiver cirrhosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christopher B. Tan Sadat Rashid Dhyan Rajan Wondwoosen Gebre Paul Mustacchia |
spellingShingle |
Christopher B. Tan Sadat Rashid Dhyan Rajan Wondwoosen Gebre Paul Mustacchia Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature Case Reports in Gastroenterology Portal hypertension Gastrointestinal sarcoidosis Extrapulmonary sarcoidosis Hepatic sarcoidosis and liver cirrhosis Hepatic sarcoidosis and portal hypertension Hepatic sarcoidosis Liver cirrhosis |
author_facet |
Christopher B. Tan Sadat Rashid Dhyan Rajan Wondwoosen Gebre Paul Mustacchia |
author_sort |
Christopher B. Tan |
title |
Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature |
title_short |
Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature |
title_full |
Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature |
title_fullStr |
Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature |
title_full_unstemmed |
Hepatic Sarcoidosis Presenting as Portal Hypertension and Liver Cirrhosis: Case Report and Review of the Literature |
title_sort |
hepatic sarcoidosis presenting as portal hypertension and liver cirrhosis: case report and review of the literature |
publisher |
Karger Publishers |
series |
Case Reports in Gastroenterology |
issn |
1662-0631 |
publishDate |
2012-04-01 |
description |
Systemic sarcoidosis is a disease of unknown etiology, with the liver being the third most commonly affected organ. Most cases of hepatic sarcoidosis are not clinically apparent, but a few can progress to liver cirrhosis, portal hypertension and ultimately liver failure. The diagnosis of hepatic sarcoidosis is difficult, considering that no single laboratory test or radiographic finding can definitively diagnose this systemic disease. Diagnosis of hepatic sarcoidosis relies heavily on histopathologic evaluation of two or more organs, a diagnostic modality that is invasive and may not be applicable to all patients. The treatment of hepatic sarcoidosis is challenging, with no large randomized controlled trials done to date. Physicians must be aware of the complications of hepatic sarcoidosis, and must include the same in the differential diagnosis of liver cirrhosis. We present a case of hepatic sarcoidosis complicated by portal hypertension and liver cirrhosis. |
topic |
Portal hypertension Gastrointestinal sarcoidosis Extrapulmonary sarcoidosis Hepatic sarcoidosis and liver cirrhosis Hepatic sarcoidosis and portal hypertension Hepatic sarcoidosis Liver cirrhosis |
url |
http://www.karger.com/Article/FullText/338355 |
work_keys_str_mv |
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