PEG-Chitosan Hydrogel with Tunable Stiffness for Study of Drug Response of Breast Cancer Cells

PEG-Chitosan Hydrogel with Tunable Stiffness for Study of Drug Response of Breast Cancer Cells

Mechanical properties of the extracellular matrix have a profound effect on the behavior of anchorage-dependent cells. However, the mechanisms that define the effects of matrix stiffness on cell behavior remains unclear. Therefore, the development and fabrication of synthetic matrices with well-defi...

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Bibliographic Details
Main Authors: Fei-Chien Chang, Ching-Ting Tsao, Anqi Lin, Mengying Zhang, Sheeny Lan Levengood, Miqin Zhang
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Polymers
Subjects:
hydrogel
chitosan
stiffness
modulus
tunable
extracellular matrix
Online Access:http://www.mdpi.com/2073-4360/8/4/112

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