The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

<p>Abstract</p> <p>Background</p> <p>Brain tissue from patients with Alzheimer's disease has shown an increase of phosphorylation of Tyr-682, located on the conserved Y682ENPTY motif, and Thr-668 residues, both in the intracellular domain (AID) of amyloid β precurs...

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Bibliographic Details
Main Authors: D'Adamio Luciano, Zhou Dawang, Tamayev Robert
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/28