Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes

Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes

A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermedi...

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Bibliographic Details
Main Authors: Anjiang Zhang, Lisheng Ding, Changhua Ge, Huanan Hu
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
Vilsmeier-Haack reagent
phenylhydrazine
phenylhydrazone
1H-pyrazole-4-carbaldehyde
Online Access:http://www.mdpi.com/1420-3049/15/10/7472/
Description
Summary:A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermediate 5b was investigated by X-ray crystallography.
ISSN:1420-3049

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