Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes

A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermedi...

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Main Authors: Anjiang Zhang, Lisheng Ding, Changhua Ge, Huanan Hu
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/10/7472/
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spelling doaj-b9a123eb10524006a76f89158855915b2020-11-24T21:05:19ZengMDPI AGMolecules1420-30492010-10-0115107472748110.3390/molecules15107472Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydesAnjiang ZhangLisheng DingChanghua GeHuanan HuA series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermediate 5b was investigated by X-ray crystallography. http://www.mdpi.com/1420-3049/15/10/7472/Vilsmeier-Haack reagentphenylhydrazinephenylhydrazone1H-pyrazole-4-carbaldehyde
collection DOAJ
language English
format Article
sources DOAJ
author Anjiang Zhang
Lisheng Ding
Changhua Ge
Huanan Hu
spellingShingle Anjiang Zhang
Lisheng Ding
Changhua Ge
Huanan Hu
Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
Molecules
Vilsmeier-Haack reagent
phenylhydrazine
phenylhydrazone
1H-pyrazole-4-carbaldehyde
author_facet Anjiang Zhang
Lisheng Ding
Changhua Ge
Huanan Hu
author_sort Anjiang Zhang
title Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
title_short Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
title_full Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
title_fullStr Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
title_full_unstemmed Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes
title_sort synthesis of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1h-pyrazole-4-carbaldehydes
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2010-10-01
description A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermediate 5b was investigated by X-ray crystallography.
topic Vilsmeier-Haack reagent
phenylhydrazine
phenylhydrazone
1H-pyrazole-4-carbaldehyde
url http://www.mdpi.com/1420-3049/15/10/7472/
work_keys_str_mv AT anjiangzhang synthesisofnovel126dichloro4trifluoromethylphenyl3aryl1hpyrazole4carbaldehydes
AT lishengding synthesisofnovel126dichloro4trifluoromethylphenyl3aryl1hpyrazole4carbaldehydes
AT changhuage synthesisofnovel126dichloro4trifluoromethylphenyl3aryl1hpyrazole4carbaldehydes
AT huananhu synthesisofnovel126dichloro4trifluoromethylphenyl3aryl1hpyrazole4carbaldehydes
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