Toxicity evaluation of Eleutherine plicata Herb. extracts and possible cell death mechanism

Toxicity evaluation of Eleutherine plicata Herb. extracts and possible cell death mechanism

Eleutherine plicata has been shown to be a promising medicinal plant, and its activity has been associated with naphthoquinones. The present study aimed at evaluating the cytotoxicity, genotoxicity, and oral toxicity of the ethanol extract (EEEp), dichloromethane fraction (FDMEp) of E. plicata, and...

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Bibliographic Details
Main Authors: Antonio Rafael Quadros Gomes, Natasha Costa da Rocha Galucio, Kelly Cristina Oliveira de Albuquerque, Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Ana Laura Gadelha Castro, Valdicley Vieira Vale, Marcelo Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfeta, Liliane Almeida Carneiro, Sandro Percario, Maria Fâni Dolabela
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Eleutherine plicata
Toxicity
Isoeleutherin
Eleutherin
Eleutherol
Caspase-8
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001426

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http://www.sciencedirect.com/science/article/pii/S2214750021001426

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