Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.
Cystatin C (CysC) expression in the brain is elevated in human patients with epilepsy, in animal models of neurodegenerative conditions, and in response to injury, but whether up-regulated CysC expression is a manifestation of neurodegeneration or a cellular repair response is not understood. This s...
Main Authors: | Belen Tizon, Susmita Sahoo, Haung Yu, Sebastien Gauthier, Asok R Kumar, Panaiyur Mohan, Matthew Figliola, Monika Pawlik, Anders Grubb, Yasuo Uchiyama, Urmi Bandyopadhyay, Ana Maria Cuervo, Ralph A Nixon, Efrat Levy |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-03-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2843718?pdf=render |
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