Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution
A ratiometric fluorescent probe based on a Cd2+–ACAQ complex was designed and demonstrated for the chemo- and enantioselective detection of cysteine in 99:1 buffered HEPES:ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an e...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2011-11-01
|
| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.7.176 |
| id |
doaj-b9f7c912a5f14dc6a5dfaf6e258f2f4c |
|---|---|
| record_format |
Article |
| spelling |
doaj-b9f7c912a5f14dc6a5dfaf6e258f2f4c2021-03-02T08:57:29ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972011-11-01711508151510.3762/bjoc.7.1761860-5397-7-176Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solutionXiao-bo Zhou0Wing-Hong Chan1Albert W. M. Lee2Chi-Chung Yeung3Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaA ratiometric fluorescent probe based on a Cd2+–ACAQ complex was designed and demonstrated for the chemo- and enantioselective detection of cysteine in 99:1 buffered HEPES:ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.https://doi.org/10.3762/bjoc.7.176chemosensorD-cysteineenantioselectivityfluorescenceratiometric |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Xiao-bo Zhou Wing-Hong Chan Albert W. M. Lee Chi-Chung Yeung |
| spellingShingle |
Xiao-bo Zhou Wing-Hong Chan Albert W. M. Lee Chi-Chung Yeung Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution Beilstein Journal of Organic Chemistry chemosensor D-cysteine enantioselectivity fluorescence ratiometric |
| author_facet |
Xiao-bo Zhou Wing-Hong Chan Albert W. M. Lee Chi-Chung Yeung |
| author_sort |
Xiao-bo Zhou |
| title |
Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution |
| title_short |
Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution |
| title_full |
Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution |
| title_fullStr |
Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution |
| title_full_unstemmed |
Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution |
| title_sort |
ratiometric fluorescent probe for enantioselective detection of d-cysteine in aqueous solution |
| publisher |
Beilstein-Institut |
| series |
Beilstein Journal of Organic Chemistry |
| issn |
1860-5397 |
| publishDate |
2011-11-01 |
| description |
A ratiometric fluorescent probe based on a Cd2+–ACAQ complex was designed and demonstrated for the chemo- and enantioselective detection of cysteine in 99:1 buffered HEPES:ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys. |
| topic |
chemosensor D-cysteine enantioselectivity fluorescence ratiometric |
| url |
https://doi.org/10.3762/bjoc.7.176 |
| work_keys_str_mv |
AT xiaobozhou ratiometricfluorescentprobeforenantioselectivedetectionofdcysteineinaqueoussolution AT winghongchan ratiometricfluorescentprobeforenantioselectivedetectionofdcysteineinaqueoussolution AT albertwmlee ratiometricfluorescentprobeforenantioselectivedetectionofdcysteineinaqueoussolution AT chichungyeung ratiometricfluorescentprobeforenantioselectivedetectionofdcysteineinaqueoussolution |
| _version_ |
1724240327164821504 |