Direct visualization of a Fe(IV)–OH intermediate in a heme enzyme
The nature of the ferryl intermediate generated in reactions catalysed by heme-containing enzymes is uncertain, due to the ambiguity of X-ray crystallography data. Here, the authors apply neutron diffraction, kinetics and other spectroscopy to directly observe a protonated ferryl intermediate in a h...
Full description
Bibliographic Details
Main Authors: |
Hanna Kwon,
Jaswir Basran,
Cecilia M. Casadei,
Alistair J. Fielding,
Tobias E. Schrader,
Andreas Ostermann,
Juliette M. Devos,
Pierre Aller,
Matthew P. Blakeley,
Peter C. E. Moody,
Emma L. Raven |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2016-11-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/ncomms13445
|