Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate

Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate

Methods for direct dehydrative glycosylations of carbohydrate hemiacetals catalyzed by diphenylammonium triflate under microwave irradiation are described. Both armed and disarmed glycosyl-C1-hemiacetal donors were efficiently glycosylated in moderate to excellent yields without the need for any dry...

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Bibliographic Details
Main Authors: Mei-Yuan Hsu, Sarah Lam, Chia-Hui Wu, Mei-Huei Lin, Su-Ching Lin, Cheng-Chung Wang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
carbohydrates
dehydration
glycosylation
homogeneous catalysis microwave chemistry
Online Access:https://www.mdpi.com/1420-3049/25/5/1103
Description
Summary:Methods for direct dehydrative glycosylations of carbohydrate hemiacetals catalyzed by diphenylammonium triflate under microwave irradiation are described. Both armed and disarmed glycosyl-C1-hemiacetal donors were efficiently glycosylated in moderate to excellent yields without the need for any drying agents and stoichiometric additives. This method has been successfully applied to a solid-phase glycosylation.
ISSN:1420-3049

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