Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth
Introduction: The usage of Calcium hydroxide (CaOH2) has wide applications due to the property of osteo-inductive, protective, and antibacterial actions. However, it is not used in primary teeth, as it fails to form reparative dentin and the exact mechanism has not been explained. The hypothesis: Th...
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2015-01-01
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doaj-ba2f68b7c1654a17841145529a8539a42020-11-25T00:21:28ZengWolters Kluwer Medknow PublicationsDental Hypotheses2155-82132015-01-01616910.4103/2155-8213.150863Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teethG R RaviR V SubramanyamIntroduction: The usage of Calcium hydroxide (CaOH2) has wide applications due to the property of osteo-inductive, protective, and antibacterial actions. However, it is not used in primary teeth, as it fails to form reparative dentin and the exact mechanism has not been explained. The hypothesis: The authors propose an explanation that lack of dentin bridge formation in response to (CaOH2) in primary teeth could be multifactorial: inability of the deciduous stem cells to generate complete dentin-pulp-like tissue; the absence of calcium-magnesium-dependent adenosine triphosphatase (Ca-Mg ATPase) in the odontoblasts; the pre-existing predilection of deciduous dentine pulp to form odontoclasts; the solubility of (CaOH2). Evaluation of the hypothesis: The hypothesis discusses the innate traits of the deciduous stem cells that lack the ability to form the dentin bridge, the absence of Ca-Mg ATPase enzyme and increased solubility of (CaOH2) together fail to stimulate the odontoblasts. Alternatively, pre-existing progenitor cells with proclivity to change into odontoclasts may cause internal resorption and hamper formation of reparative dentin.http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2015;volume=6;issue=1;spage=6;epage=9;aulast=RaviCalcium hydroxideCa-Mg ATPasedentin bridgedeciduous teethprimary teethtooth resorption |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
G R Ravi R V Subramanyam |
spellingShingle |
G R Ravi R V Subramanyam Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth Dental Hypotheses Calcium hydroxide Ca-Mg ATPase dentin bridge deciduous teeth primary teeth tooth resorption |
author_facet |
G R Ravi R V Subramanyam |
author_sort |
G R Ravi |
title |
Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
title_short |
Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
title_full |
Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
title_fullStr |
Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
title_full_unstemmed |
Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
title_sort |
possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth |
publisher |
Wolters Kluwer Medknow Publications |
series |
Dental Hypotheses |
issn |
2155-8213 |
publishDate |
2015-01-01 |
description |
Introduction: The usage of Calcium hydroxide (CaOH2) has wide applications due to the property of osteo-inductive, protective, and antibacterial actions. However, it is not used in primary teeth, as it fails to form reparative dentin and the exact mechanism has not been explained. The hypothesis: The authors propose an explanation that lack of dentin bridge formation in response to (CaOH2) in primary teeth could be multifactorial: inability of the deciduous stem cells to generate complete dentin-pulp-like tissue; the absence of calcium-magnesium-dependent adenosine triphosphatase (Ca-Mg ATPase) in the odontoblasts; the pre-existing predilection of deciduous dentine pulp to form odontoclasts; the solubility of (CaOH2). Evaluation of the hypothesis: The hypothesis discusses the innate traits of the deciduous stem cells that lack the ability to form the dentin bridge, the absence of Ca-Mg ATPase enzyme and increased solubility of (CaOH2) together fail to stimulate the odontoblasts. Alternatively, pre-existing progenitor cells with proclivity to change into odontoclasts may cause internal resorption and hamper formation of reparative dentin. |
topic |
Calcium hydroxide Ca-Mg ATPase dentin bridge deciduous teeth primary teeth tooth resorption |
url |
http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2015;volume=6;issue=1;spage=6;epage=9;aulast=Ravi |
work_keys_str_mv |
AT grravi possiblemechanismsoflackofdentinbridgeformationinresponsetocalciumhydroxideinprimaryteeth AT rvsubramanyam possiblemechanismsoflackofdentinbridgeformationinresponsetocalciumhydroxideinprimaryteeth |
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