Non-canonical reader modules of BAZ1A promote recovery from DNA damage

Non-canonical reader modules of BAZ1A promote recovery from DNA damage

ISWI chromatin remodelers regulate DNA accessibility and have been implicated in DNA damage repair. Here, the authors uncover functions, in response to DNA damage, for the bromodomain of the ISWI subunit BAZ1B and for the non-canonical PHD and bromodomain modules of the paralog BAZ1A.

Bibliographic Details
Main Authors: Mariano Oppikofer, Meredith Sagolla, Benjamin Haley, Hui-Min Zhang, Sarah K. Kummerfeld, Jawahar Sudhamsu, E. Megan Flynn, Tianyi Bai, Jennifer Zhang, Claudio Ciferri, Andrea G. Cochran
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00866-0
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spelling doaj-ba2fcffc416342099321e94a0269cffd2021-05-11T07:36:34ZengNature Publishing GroupNature Communications2041-17232017-10-018111510.1038/s41467-017-00866-0Non-canonical reader modules of BAZ1A promote recovery from DNA damageMariano Oppikofer0Meredith Sagolla1Benjamin Haley2Hui-Min Zhang3Sarah K. Kummerfeld4Jawahar Sudhamsu5E. Megan Flynn6Tianyi Bai7Jennifer Zhang8Claudio Ciferri9Andrea G. Cochran10Department of Early Discovery Biochemistry, Genentech, Inc.Center for Advanced Light Microscopy, Genentech, Inc.Department of Molecular Biology, Genentech, Inc.Protein Analytical Chemistry, Genentech, Inc.Department of Bioinformatics and Computational Biology, Genentech, Inc.Department of Structural Biology, Genentech, Inc.Department of Early Discovery Biochemistry, Genentech, Inc.Department of Structural Biology, Genentech, Inc.Protein Analytical Chemistry, Genentech, Inc.Department of Structural Biology, Genentech, Inc.Department of Early Discovery Biochemistry, Genentech, Inc.ISWI chromatin remodelers regulate DNA accessibility and have been implicated in DNA damage repair. Here, the authors uncover functions, in response to DNA damage, for the bromodomain of the ISWI subunit BAZ1B and for the non-canonical PHD and bromodomain modules of the paralog BAZ1A.https://doi.org/10.1038/s41467-017-00866-0
collection DOAJ
language English
format Article
sources DOAJ
author Mariano Oppikofer
Meredith Sagolla
Benjamin Haley
Hui-Min Zhang
Sarah K. Kummerfeld
Jawahar Sudhamsu
E. Megan Flynn
Tianyi Bai
Jennifer Zhang
Claudio Ciferri
Andrea G. Cochran
spellingShingle Mariano Oppikofer
Meredith Sagolla
Benjamin Haley
Hui-Min Zhang
Sarah K. Kummerfeld
Jawahar Sudhamsu
E. Megan Flynn
Tianyi Bai
Jennifer Zhang
Claudio Ciferri
Andrea G. Cochran
Non-canonical reader modules of BAZ1A promote recovery from DNA damage
Nature Communications
author_facet Mariano Oppikofer
Meredith Sagolla
Benjamin Haley
Hui-Min Zhang
Sarah K. Kummerfeld
Jawahar Sudhamsu
E. Megan Flynn
Tianyi Bai
Jennifer Zhang
Claudio Ciferri
Andrea G. Cochran
author_sort Mariano Oppikofer
title Non-canonical reader modules of BAZ1A promote recovery from DNA damage
title_short Non-canonical reader modules of BAZ1A promote recovery from DNA damage
title_full Non-canonical reader modules of BAZ1A promote recovery from DNA damage
title_fullStr Non-canonical reader modules of BAZ1A promote recovery from DNA damage
title_full_unstemmed Non-canonical reader modules of BAZ1A promote recovery from DNA damage
title_sort non-canonical reader modules of baz1a promote recovery from dna damage
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-10-01
description ISWI chromatin remodelers regulate DNA accessibility and have been implicated in DNA damage repair. Here, the authors uncover functions, in response to DNA damage, for the bromodomain of the ISWI subunit BAZ1B and for the non-canonical PHD and bromodomain modules of the paralog BAZ1A.
url https://doi.org/10.1038/s41467-017-00866-0
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