Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG do...
Main Authors: | Hermann Broder Schmidt, Dirk Görlich |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-01-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/04251 |
Similar Items
-
Nup2 and a Newly Discovered Nuclear Pore Complex Protein, NupA, Function at Mitotic Chromatin Controlled by the NIMA Kinase
by: Markossian, Sarine W.
Published: (2011) -
Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes
by: Masahiro Oka, et al.
Published: (2016-01-01) -
Implication of the Nup133 subunit of nuclear pores in cell division and differentiation : partners and mechanisms.
by: Berto, Alessandro
Published: (2017) -
The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype
by: Masaki Makise, et al.
Published: (2018-05-01) -
Nup358 interacts with Dishevelled and aPKC to regulate neuronal polarity
by: Pankhuri Vyas, et al.
Published: (2013-10-01)