Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review
The frequency of concomitant adnexal tumors in pregnancy is reported to be at 0.15–5.7%, while ovarian cancer complicates 1 in 15,000 to 1 in 32,000 pregnancies, being the second most common gynecologic cancer diagnosed during pregnancy. The aim of this review is to discuss the problem of ovarian ca...
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doaj-ba805d48af9b4425969232f88d7f78c22020-12-17T00:01:38ZengMDPI AGCancers2072-66942020-12-01123795379510.3390/cancers12123795Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive ReviewDominik Franciszek Dłuski0Radzisław Mierzyński1Elżbieta Poniedziałek-Czajkowska2Bożena Leszczyńska-Gorzelak3Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Lubelskie Region, PolandChair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Lubelskie Region, PolandChair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Lubelskie Region, PolandChair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Lubelskie Region, PolandThe frequency of concomitant adnexal tumors in pregnancy is reported to be at 0.15–5.7%, while ovarian cancer complicates 1 in 15,000 to 1 in 32,000 pregnancies, being the second most common gynecologic cancer diagnosed during pregnancy. The aim of this review is to discuss the problem of ovarian cancer complicating pregnancy and the current recommendations for diagnostics and treatment, with an emphasis on the risk to the fetus. A detailed analysis of the literature found in the PubMed and MEDLINE databases using the keywords “ovarian cancer”, “ovarian malignancy”, “adnexal masses”, “ovarian tumor” and “pregnancy” was performed. There were no studies on a large series of pregnant women treated for ovarian malignancies and the management has not been well established. The diagnostics and therapeutic procedures need to be individualized with respect to the histopathology of the tumor, its progression, the gestational age at the time of diagnosis and the mother’s decisions regarding pregnancy preservation. The multidisciplinary cooperation of specialists in perinatal medicine, gynecological oncology, chemotherapy, neonatology and psychology seems crucial in order to obtain the best possible maternal and neonatal outcomes.https://www.mdpi.com/2072-6694/12/12/3795adnexal massesmanagement in pregnancyovarian cancerovarian malignancyovarian tumorpregnancy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dominik Franciszek Dłuski Radzisław Mierzyński Elżbieta Poniedziałek-Czajkowska Bożena Leszczyńska-Gorzelak |
spellingShingle |
Dominik Franciszek Dłuski Radzisław Mierzyński Elżbieta Poniedziałek-Czajkowska Bożena Leszczyńska-Gorzelak Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review Cancers adnexal masses management in pregnancy ovarian cancer ovarian malignancy ovarian tumor pregnancy |
author_facet |
Dominik Franciszek Dłuski Radzisław Mierzyński Elżbieta Poniedziałek-Czajkowska Bożena Leszczyńska-Gorzelak |
author_sort |
Dominik Franciszek Dłuski |
title |
Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review |
title_short |
Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review |
title_full |
Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review |
title_fullStr |
Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review |
title_full_unstemmed |
Ovarian Cancer and Pregnancy—A Current Problem in Perinatal Medicine: A Comprehensive Review |
title_sort |
ovarian cancer and pregnancy—a current problem in perinatal medicine: a comprehensive review |
publisher |
MDPI AG |
series |
Cancers |
issn |
2072-6694 |
publishDate |
2020-12-01 |
description |
The frequency of concomitant adnexal tumors in pregnancy is reported to be at 0.15–5.7%, while ovarian cancer complicates 1 in 15,000 to 1 in 32,000 pregnancies, being the second most common gynecologic cancer diagnosed during pregnancy. The aim of this review is to discuss the problem of ovarian cancer complicating pregnancy and the current recommendations for diagnostics and treatment, with an emphasis on the risk to the fetus. A detailed analysis of the literature found in the PubMed and MEDLINE databases using the keywords “ovarian cancer”, “ovarian malignancy”, “adnexal masses”, “ovarian tumor” and “pregnancy” was performed. There were no studies on a large series of pregnant women treated for ovarian malignancies and the management has not been well established. The diagnostics and therapeutic procedures need to be individualized with respect to the histopathology of the tumor, its progression, the gestational age at the time of diagnosis and the mother’s decisions regarding pregnancy preservation. The multidisciplinary cooperation of specialists in perinatal medicine, gynecological oncology, chemotherapy, neonatology and psychology seems crucial in order to obtain the best possible maternal and neonatal outcomes. |
topic |
adnexal masses management in pregnancy ovarian cancer ovarian malignancy ovarian tumor pregnancy |
url |
https://www.mdpi.com/2072-6694/12/12/3795 |
work_keys_str_mv |
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