The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs

Back pain: overactive protein causes disc breakdown Treatments targeting a protein that is overexpressed in damaged spinal cartilage could ease degenerative conditions associated with lower back pain. The intervertebral discs are complex cartilage tissues that absorb forces while allowing the motion...

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Bibliographic Details
Main Authors: Bao Huang, Yongqing He, Shengwen Li, Xiaoan Wei, Junhui Liu, Zhi Shan, Yue Huang, Jian Chen, Fengdong Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0441-x

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