Quantitative Determination of Benzalconium Chloride in the Naltrexone Hydrochloride Nasal Spray

Quantitative Determination of Benzalconium Chloride in the Naltrexone Hydrochloride Nasal Spray

Introduction. Benzalkonium chloride is widely used as a conservation agent in medicines. For quantitative determination, the methods described in the European and American Pharmacopoeias by chromatography using columns with nitrile sorbent are often used. However, in order to unify the methods and s...

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Bibliographic Details
Main Authors:	Yu. M. Domnina, V. V. Suslov, S. A. Kedik, E. V. Vorfolomeeva, A. V. Meleshko
Format:	Article
Language:	Russian
Published:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2020-11-01
Series:	Разработка и регистрация лекарственных средств
Subjects:	nasal spray naltrexone high-performance liquid chromatography validation gradient mode
Online Access:	https://www.pharmjournal.ru/jour/article/view/838

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