Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber
Purpose: To evaluate the outcome of a nonvalved Aurolab aqueous drainage implant (AADI) in the management of refractory glaucoma. Methods: Retrospective case series of patients with refractory glaucoma underwent AADI implantation in posterior segment (PS group) or anterior chamber (AC group) with mi...
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doaj-bab23ab6a5f64cc48306a99bc087904f2020-11-25T01:33:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892019-01-016781303130810.4103/ijo.IJO_1341_18Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamberDevendra MaheshwariShylesh DabkeSindhushree RajagopalMohideen A KadarRengappa RamakrishnanPurpose: To evaluate the outcome of a nonvalved Aurolab aqueous drainage implant (AADI) in the management of refractory glaucoma. Methods: Retrospective case series of patients with refractory glaucoma underwent AADI implantation in posterior segment (PS group) or anterior chamber (AC group) with minimum follow-up of 1 year. Primary outcome criterion was success, defined as intraocular pressure (IOP) <18 or >6 mm Hg or IOP reduced to <20% from baseline, for two consecutive visits after 3 months. Failure was defined as inability to meet IOP criteria, any additional glaucoma surgery, loss of light perception, and implant explantation. Secondary outcome criteria compared groups based on mean IOP, mean glaucoma medication use, best-corrected visual acuity, and complications at each postoperative visit. Results: In the AC and PS group of 64 patients, 32 tubes each were placed. Preoperative mean IOP was 37.41 ± 8.6 and 43.38 ± 10.3 mm Hg in AC and PS, respectively. Postoperatively IOP reduced to 14.22 ± 4.9 and 15.21 ± 8.1 mm Hg in AC and PS groups, respectively (P < 0.001). Preoperative mean antiglaucoma medication changed from 2.56 ± 0.9 and 3.44 ± 0.5 to 1.03 ± 0.9 and 1.67 ± 0.5 in AC and PS, respectively, postoperatively (P < 0.001). No significant change in VA was noted in either group. At 12 months, success rate was 84% in AC group and 72% in PS group, with PS group having 2.63 times higher hazard (risk) of failure than AC group. Conclusion: AADI implantation in PS or AC is a safe and effective method for IOP control in refractory glaucoma with its low cost being of significance in developing countries.http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=8;spage=1303;epage=1308;aulast=MaheshwariAurolab aqueous drainage implantintraocular pressurenonvalved glaucoma drainage implantrefractory glaucoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Devendra Maheshwari Shylesh Dabke Sindhushree Rajagopal Mohideen A Kadar Rengappa Ramakrishnan |
spellingShingle |
Devendra Maheshwari Shylesh Dabke Sindhushree Rajagopal Mohideen A Kadar Rengappa Ramakrishnan Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber Indian Journal of Ophthalmology Aurolab aqueous drainage implant intraocular pressure nonvalved glaucoma drainage implant refractory glaucoma |
author_facet |
Devendra Maheshwari Shylesh Dabke Sindhushree Rajagopal Mohideen A Kadar Rengappa Ramakrishnan |
author_sort |
Devendra Maheshwari |
title |
Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber |
title_short |
Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber |
title_full |
Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber |
title_fullStr |
Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber |
title_full_unstemmed |
Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber |
title_sort |
clinical outcome of a nonvalved aurolab aqueous drainage implant in posterior segment versus anterior chamber |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2019-01-01 |
description |
Purpose: To evaluate the outcome of a nonvalved Aurolab aqueous drainage implant (AADI) in the management of refractory glaucoma. Methods: Retrospective case series of patients with refractory glaucoma underwent AADI implantation in posterior segment (PS group) or anterior chamber (AC group) with minimum follow-up of 1 year. Primary outcome criterion was success, defined as intraocular pressure (IOP) <18 or >6 mm Hg or IOP reduced to <20% from baseline, for two consecutive visits after 3 months. Failure was defined as inability to meet IOP criteria, any additional glaucoma surgery, loss of light perception, and implant explantation. Secondary outcome criteria compared groups based on mean IOP, mean glaucoma medication use, best-corrected visual acuity, and complications at each postoperative visit. Results: In the AC and PS group of 64 patients, 32 tubes each were placed. Preoperative mean IOP was 37.41 ± 8.6 and 43.38 ± 10.3 mm Hg in AC and PS, respectively. Postoperatively IOP reduced to 14.22 ± 4.9 and 15.21 ± 8.1 mm Hg in AC and PS groups, respectively (P < 0.001). Preoperative mean antiglaucoma medication changed from 2.56 ± 0.9 and 3.44 ± 0.5 to 1.03 ± 0.9 and 1.67 ± 0.5 in AC and PS, respectively, postoperatively (P < 0.001). No significant change in VA was noted in either group. At 12 months, success rate was 84% in AC group and 72% in PS group, with PS group having 2.63 times higher hazard (risk) of failure than AC group. Conclusion: AADI implantation in PS or AC is a safe and effective method for IOP control in refractory glaucoma with its low cost being of significance in developing countries. |
topic |
Aurolab aqueous drainage implant intraocular pressure nonvalved glaucoma drainage implant refractory glaucoma |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=8;spage=1303;epage=1308;aulast=Maheshwari |
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