Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38

Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38

Discoidin domain receptor 1 (<i>Drd1</i>) is a collagen-binding membrane protein, but its role in osteoblasts during osteogenesis remains undefined. We generated inducible osteoblast-specific <i>Ddr1</i> knockout (OKOΔ<i>Ddr1</i>) mice; their stature at birth, bod...

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Bibliographic Details
Main Authors: Liang-Yin Chou, Chung-Hwan Chen, Shu-Chun Chuang, Tsung-Lin Cheng, Yi-Hsiung Lin, Hsin-Chiao Chou, Yin-Chih Fu, Yan-Hsiung Wang, Chau-Zen Wang
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
bone
discoidin domain receptor 1
DDR1
osteoblast
osteogenesis
bone development
Online Access:https://www.mdpi.com/1422-0067/21/19/7210

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