Integrate GWAS, eQTL, and mQTL Data to Identify Alzheimer’s Disease-Related Genes

Integrate GWAS, eQTL, and mQTL Data to Identify Alzheimer’s Disease-Related Genes

It is estimated that the impact of related genes on the risk of Alzheimer’s disease (AD) is nearly 70%. Identifying candidate causal genes can help treatment and diagnosis. The maturity of sequencing technology and the reduction of cost make genome-wide association study (GWAS) become an important m...

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Bibliographic Details
Main Authors: Tianyi Zhao, Yang Hu, Tianyi Zang, Yadong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Genetics
Subjects:
Alzheimer’s disease
Mendelian randomization
GWAS
eQTL
mQTL
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01021/full

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