Neonatal gipertireotropinemiya – an indicator of the severity of iodine deficiency in the population?

• Main Authors: Ludmila Aleksandrovna Suplotova, Olga Borisovna Makarova, Larisa Sergeevna Kovalzhina
• Format: Article
• Language: Russian
• Published: Endocrinology Research Centre 2015-11-01
• Series: Клиническая и экспериментальная тиреоидология
• Subjects: iodine deficiency; neonatal tsh; prevention group; tyumen region; awareness.
• Online Access: https://cet-endojournals.ru/ket/article/viewFile/7580/5571
• ISSN: 1995-5472; 2310-3787

Aims. Rate the severity of iodine deficiency and the effectiveness of iodine prophylaxis in the Tyumen region on the basis of the criterion of neonatal hyperthyreotropinemy than 5 mU/l for the period from 1994–2014 and to determine the significance of the indicator as the monitoring of iodine deficiency in the population. Materials and methods. Analysis of screening for congenital hypothyroidism in the period from 1994–2014’s was performed in Tyumen region as an example of the region with implemented a program of prevention of iodine deficiency. Consider the views pregnant women and mothers of children of school age in the prevention of iodine deficiency by the survey. Results. In the process of implementation of regional programs for the prevention of iodine deficiency was a significant reduction in the incidence of neonatal TSH above 5 mU/l from 44.7% in 1995 to 5% in 2013. Pregnant women use of drugs iodine on group prevention iodine deficiency unequal conditions with a population for sources of iodine, so there is open the question of objective criteria neonatal TSH 5 mU/l, as an indicator of the severity of iodine deficiency in the territory. Correlation analysis of the severity indicators of iodine deficiency showed that in the region with implementing a program of iodine prophylaxis in group of pregnant women, indicator iodine deficiency – neonatal TSH 5 mU/l can be used to assess the severity of iodine deficiency in a population of pregnant women only. Revealed low awareness of pregnant women (61%) and mothers of pupils (66%) of the problem of iodine deficiency. Awareness about the means of prevention is higher. For example, 78% of respondents noted “the use of iodized salt”. An important feature observed in the prevention of iodine deficiency are different models of behavior: pregnant women under medical supervision implement prevention group using drugs iodine, and women in the status of “parent” does not have this preventive practice. The proportion of respondents using iodized salt was not significantly different. Conclusions. Therefore, pregnant (lactating) women and their newborn babies within the group prophylaxis have an advantage over children, students and their parents in the prevention of iodine deficiency in the territory endemic for iodine.