Imaging of microglia in patients with neurodegenerative disorders

Imaging of microglia in patients with neurodegenerative disorders

Microglia constitute the main immune defense in the central nervous system. In response to neuronal injury, microglia become activated, acquire phagocytic properties and release a wide range of pro-inflammatory mediators that are essential for the annihilation of the neuronal insult. Although the...

Full description

Bibliographic Details
Main Authors:	Marios ePolitis, Paul eSu, Paola ePiccini
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-05-01
Series:	Frontiers in Pharmacology
Subjects:	Dementia Microglia Multiple Sclerosis Parkinson PET Huntington
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00096/full

Similar Items

Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: An in vivo [(11)C](R)-PK11195-PET pilot study
by: Paolo Giannetti, et al.
Published: (2014-05-01)

Chatting with the neighbors: Crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders
by: Niko eHensel, et al.
Published: (2015-06-01)

Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers
by: Marios Politis, et al.
Published: (2015-11-01)

Cognitive-Motor Interference in Neurodegenerative Disease: A Narrative Review and Implications for Clinical Management
by: Tara L. McIsaac, et al.
Published: (2018-10-01)

The Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (CNS) Autoimmunity
by: Kaitlyn K. Thompson, et al.
Published: (2017-02-01)

Orexinergic System in Neurodegenerative Diseases
by: Qinqin Wang, et al.
Published: (2021-08-01)

Microglia in Multiple Sclerosis: Friend or Foe?
by: Brooke L. Guerrero, et al.
Published: (2020-03-01)

Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway
by: Nóra Török, et al.
Published: (2020-12-01)

Old Drugs as New Treatments for Neurodegenerative Diseases
by: Fernando Durães, et al.
Published: (2018-05-01)

Retinal and Brain Microglia in Multiple Sclerosis and Neurodegeneration
by: Soyoung Choi, et al.
Published: (2021-06-01)

Proteotoxicity and Neurodegenerative Diseases
by: Clara Ruz, et al.
Published: (2020-08-01)

Histone Methylation Regulation in Neurodegenerative Disorders
by: Balapal S. Basavarajappa, et al.
Published: (2021-04-01)

Ubiquitin Pathways in Neurodegenerative Disease
by: Graham eAtkin, et al.
Published: (2014-07-01)

DNA methylation, a hand behind neurodegenerative disease
by: Haoyang eLu, et al.
Published: (2013-12-01)

Predementia states and dementia in young people
by: A.A. Smirnov, et al.
Published: (2014-06-01)

Exploring the role of microglia in mood disorders associated with experimental multiple sclerosis
by: Antonietta eGentile, et al.
Published: (2015-06-01)

Circadian and Sleep Dysfunctions in Neurodegenerative Disorders—An Update
by: Karim Fifel, et al.
Published: (2021-01-01)

The Role of Microglia and Astrocytes in Huntington’s Disease
by: Thulani H. Palpagama, et al.
Published: (2019-10-01)

Elusive roles for reactive astrocytes in neurodegenerative diseases
by: Lucile eBen Haim, et al.
Published: (2015-08-01)

Effects of exercise on sleep in neurodegenerative disease
by: Adeel A. Memon, et al.
Published: (2020-07-01)

Current understanding of the glial response to disorders of the aging CNS
by: Francesca eCicchetti, et al.
Published: (2012-05-01)

Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers
by: Nicola Pavese, et al.
Published: (2010-02-01)

Mitophagy Regulates Neurodegenerative Diseases
by: Xufeng Cen, et al.
Published: (2021-07-01)

Fibrotic Scar in Neurodegenerative Diseases
by: Nadia D'Ambrosi, et al.
Published: (2020-08-01)

Clinical use of biomarkers in neurodegenerative disorders
Published: (2014)

Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination
by: Álvaro Moreno-García, et al.
Published: (2020-08-01)

The potential of epigenetic therapies in neurodegenerative diseases
by: Fabio eCoppedè
Published: (2014-07-01)

Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism
by: Pauline Vercruysse, et al.
Published: (2018-01-01)

High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis
by: Anneke Miedema, et al.
Published: (2020-10-01)

Dynamic Responses of Microglia in Animal Models of Multiple Sclerosis
by: Melanie J. Plastini, et al.
Published: (2020-08-01)

Biomarkers in neurodegenerative disorders: translating research into clinical practice
by: Manuel eMenéndez-González, et al.
Published: (2014-10-01)

Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases
by: Daniel A. Ryskamp, et al.
Published: (2019-08-01)

The established and emerging roles of astrocytes and microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
by: Rowan Andrew Warren Radford, et al.
Published: (2015-10-01)

Targeting cannabinoid CB2 receptors in the Central Nervous System. Medicinal chemistry approaches with focus on neurodegenerative disorders
by: Gema Navarro, et al.
Published: (2016-09-01)

Methods for assessing selected disorders of the autonomic nervous system in neurodegenerative diseases
by: Karolina Kubiak, et al.
Published: (2018-12-01)

Microglia: The Missing Link to Decipher and Therapeutically Control MS Progression?
by: Anastasia Geladaris, et al.
Published: (2021-03-01)

Purinergic Receptors in Neurological Diseases With Motor Symptoms: Targets for Therapy
by: Ágatha Oliveira-Giacomelli, et al.
Published: (2018-04-01)

Serotonergic mediated body mass index changes in Parkinson's disease
by: Marios Politis, et al.
Published: (2011-09-01)

Microglial Exosomes in Neurodegenerative Disease
by: Min Guo, et al.
Published: (2021-05-01)

A Scoping Review of Cognitive Training in Neurodegenerative Diseases via Computerized and Virtual Reality Tools: What We Know So Far
by: Stefano Lasaponara, et al.
Published: (2021-04-01)