Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection

Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection

Human immunodeficiency virus (HIV)-induced changes in immune cells during the acute phase of infection can cause irreversible immunological damage and predict the rate of disease progression. Antiretroviral therapy (ART) remains the most effective strategy for successful immune restoration in immuno...

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Bibliographic Details
Main Authors: Kewreshini K. Naidoo, Okechukwu C. Ndumnego, Nasreen Ismail, Krista L. Dong, Thumbi Ndung’u
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
antigen presenting cells
immune activation
inflammation
hyperacute HIV-1 infection
antiretroviral therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.738743/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.738743/full

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