A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2

A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2

Breast cancer is the most common type of female cancer. Reactive oxygen species (ROS) are vital in regulating signaling pathways that control cell survival and cell proliferation. Chemotherapeutic drugs such as anthracyclines induce cell death via ROS induction. Chemoresistance development is associ...

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Bibliographic Details
Main Authors: Man-Hong Leung, Ho Tsoi, Chun Gong, Ellen PS Man, Stefania Zona, Shang Yao, Eric W.-F. Lam, Ui-Soon Khoo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
splice variant bq
chemoresistance
breast cancer
nrf2
ncor2
Online Access:https://www.mdpi.com/2072-6694/12/3/533

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