Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo
Summary: A flavin-dependent enzyme quiescin Q6 sulfhydryl oxidase 1 (QSOX1) catalyzes the oxidation of thiol groups into disulfide bonds. QSOX1 is prominently expressed in the seminal plasma. However, its role in male reproduction is elusive. Here, we purified the secreted form of QSOX1, i.e., QSOX1...
Main Authors: | Tse-En Wang, Ling-Yu Yeh, Robert Kuo-Kuang Lee, Chung-Hao Lu, Tsung-Hsien Yang, Yu-Wen Kuo, Radhika Joshi, Pei-Shiue Tsai, Sheng-Hsiang Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221011354 |
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