Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice
Glucocorticoids promote muscle atrophy by inducing a class of proteins called atrogenes, resulting in reductions in muscle size and strength. In this work, we evaluated whether a mouse model with pre-existing diet-induced obesity had altered glucocorticoid responsiveness. We observed that all animal...
Main Authors: | Laura C. Gunder, Innocence Harvey, JeAnna R. Redd, Carol S. Davis, Ayat AL-Tamimi, Susan V. Brooks, Dave Bridges |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/10/420 |
Similar Items
-
Identificação de genes associados à atrofia muscular induzida pela privação de andrógeno
by: Coelho, Priscila de Oliveira
Published: (2019) -
Master Regulators of Muscle Atrophy: Role of Costamere Components
by: Luisa Gorza, et al.
Published: (2021-01-01) -
Angiotensin-(1–7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice
by: Anne Järve, et al.
Published: (2020-03-01) -
Glucocorticoid-Induced Skin Atrophy: The Old and the New
by: Niculet E, et al.
Published: (2020-12-01) -
Insulin treatment reverses the increase in atrogin-1 expression in atrophied skeletal muscles of diabetic rats with acute joint inflammation
by: Pinheiro-Dardis CM, et al.
Published: (2018-02-01)