Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women
Purpose: This study was conducted in menopausal women to determine the metabolic impact of Nigella sativa. Methods: Thirty subjects who were menopausal women within the age limit of 45-60 were participated in this study and randomly allotted into two experimental groups. The treatment group was oral...
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Tabriz University of Medical Sciences
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doaj-bb490a7e470644118f60f2c0f0cee1e22020-11-24T21:10:30ZengTabriz University of Medical Sciences Advanced Pharmaceutical Bulletin2228-58812251-73082014-03-0141293310.5681/apb.2014.005APB_977_20130614144042Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal WomenRamlah Mohamad Ibrahim0Nurul Syima Hamdan1Maznah Ismail2Suraini Mohd Saini3Saiful Nizam Abd Rashid4Latiffah Abd Latiff5Rozi Mahmud6Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Imaging, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Imaging, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Department of Imaging, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.Purpose: This study was conducted in menopausal women to determine the metabolic impact of Nigella sativa. Methods: Thirty subjects who were menopausal women within the age limit of 45-60 were participated in this study and randomly allotted into two experimental groups. The treatment group was orally administered with N. sativa seeds powder in the form of capsules at a dose of 1g per day after breakfast for period of two months and compared to control group given placebo. Anthropometric and biochemical parameters were measured at baseline, 1st month, 2nd month and a month after treatment completed to determine their body weight, serum lipid profile and fasting blood glucose (FBG). Results: The treatment group showed slight reduction with no significant difference in body weight changes of the respondents. However, significant (p<0.05) improvement was observed in total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and blood glucose (p<0.05). Conclusion: These results suggested that treatment with N. sativa exert a protective effect by improving lipid profile and blood glucose which are in higher risk to be elevated during menopausal period.http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-29.pdfNigella sativaMenopauseMetabolic syndromeHyperlipidemicHyperglycemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ramlah Mohamad Ibrahim Nurul Syima Hamdan Maznah Ismail Suraini Mohd Saini Saiful Nizam Abd Rashid Latiffah Abd Latiff Rozi Mahmud |
spellingShingle |
Ramlah Mohamad Ibrahim Nurul Syima Hamdan Maznah Ismail Suraini Mohd Saini Saiful Nizam Abd Rashid Latiffah Abd Latiff Rozi Mahmud Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women Advanced Pharmaceutical Bulletin Nigella sativa Menopause Metabolic syndrome Hyperlipidemic Hyperglycemia |
author_facet |
Ramlah Mohamad Ibrahim Nurul Syima Hamdan Maznah Ismail Suraini Mohd Saini Saiful Nizam Abd Rashid Latiffah Abd Latiff Rozi Mahmud |
author_sort |
Ramlah Mohamad Ibrahim |
title |
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women |
title_short |
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women |
title_full |
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women |
title_fullStr |
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women |
title_full_unstemmed |
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women |
title_sort |
protective effects of nigella sativa on metabolic syndrome in menopausal women |
publisher |
Tabriz University of Medical Sciences |
series |
Advanced Pharmaceutical Bulletin |
issn |
2228-5881 2251-7308 |
publishDate |
2014-03-01 |
description |
Purpose: This study was conducted in menopausal women to determine the metabolic impact of Nigella sativa.
Methods: Thirty subjects who were menopausal women within the age limit of 45-60 were participated in this study and randomly allotted into two experimental groups. The treatment group was orally administered with N. sativa seeds powder in the form of capsules at a dose of 1g per day after breakfast for period of two months and compared to control group given placebo. Anthropometric and biochemical parameters were measured at baseline, 1st month, 2nd month and a month after treatment completed to determine their body weight, serum lipid profile and fasting blood glucose (FBG).
Results: The treatment group showed slight reduction with no significant difference in body weight changes of the respondents. However, significant (p<0.05) improvement was observed in total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and blood glucose (p<0.05).
Conclusion: These results suggested that treatment with N. sativa exert a protective effect by improving lipid profile and blood glucose which are in higher risk to be elevated during menopausal period. |
topic |
Nigella sativa Menopause Metabolic syndrome Hyperlipidemic Hyperglycemia |
url |
http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-29.pdf |
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