Challenging Received Wisdom: Antidepressants and the Placebo Effect
This article explores the reaction when an article challenging received wisdom is published and covered extensively by the media (1). The article in question was a meta-analysis of antidepressant clinical trials indicating that for most patients, difference between drug and placebo was not clinicall...
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2020-12-01
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Online Access: | https://mjm.mcgill.ca/article/view/571 |
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doaj-bb5c7a8f52ea4828b9214947989857832021-01-22T03:36:11ZengMcGill UniversityMcGill Journal of Medicine1715-81252020-12-0111210.26443/mjm.v11i2.571786Challenging Received Wisdom: Antidepressants and the Placebo EffectIrving KirschThis article explores the reaction when an article challenging received wisdom is published and covered extensively by the media (1). The article in question was a meta-analysis of antidepressant clinical trials indicating that for most patients, difference between drug and placebo was not clinically significant. Reactions ranged from denial that the effects of antidepressants are so small to criticisms of the clinical trials that were analyzed. Each of these reactions is explored and countered.https://mjm.mcgill.ca/article/view/571antidepressantsplacebo |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Irving Kirsch |
spellingShingle |
Irving Kirsch Challenging Received Wisdom: Antidepressants and the Placebo Effect McGill Journal of Medicine antidepressants placebo |
author_facet |
Irving Kirsch |
author_sort |
Irving Kirsch |
title |
Challenging Received Wisdom: Antidepressants and the Placebo Effect |
title_short |
Challenging Received Wisdom: Antidepressants and the Placebo Effect |
title_full |
Challenging Received Wisdom: Antidepressants and the Placebo Effect |
title_fullStr |
Challenging Received Wisdom: Antidepressants and the Placebo Effect |
title_full_unstemmed |
Challenging Received Wisdom: Antidepressants and the Placebo Effect |
title_sort |
challenging received wisdom: antidepressants and the placebo effect |
publisher |
McGill University |
series |
McGill Journal of Medicine |
issn |
1715-8125 |
publishDate |
2020-12-01 |
description |
This article explores the reaction when an article challenging received wisdom is published and covered extensively by the media (1). The article in question was a meta-analysis of antidepressant clinical trials indicating that for most patients, difference between drug and placebo was not clinically significant. Reactions ranged from denial that the effects of antidepressants are so small to criticisms of the clinical trials that were analyzed. Each of these reactions is explored and countered. |
topic |
antidepressants placebo |
url |
https://mjm.mcgill.ca/article/view/571 |
work_keys_str_mv |
AT irvingkirsch challengingreceivedwisdomantidepressantsandtheplaceboeffect |
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