The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
Horse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle...
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doaj-bb5fe35c90b44ebf80e42c394a13efd92020-11-25T02:20:26ZengMDPI AGAnimals2076-26152019-08-019857410.3390/ani9080574ani9080574The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian HorsesMonika Stefaniuk-Szmukier0Tomasz Szmatoła1Joanna Łątka2Bogusława Długosz3Katarzyna Ropka-Molik4Department of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, PolandDepartment of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, PolandHorse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle’s cross-sectional area under the influence of contractile forces. The aim of the present study was the evaluation of transcript abundance of the telethonin (<i>TCAP</i>) gene, which is a part of the sarcomere macromolecular mechanosensory complex in the gluteus medius muscle, and the whole blood of Arabian horses during flat race training. The analysis, performed by quantitative PCR, showed an increase of <i>TCAP</i> transcripts in skeletal muscle. However, in whole blood, the transcript abundance decreased after the first stage of training and further increased after the second phase. The obtained results indicate a lack of similarity of <i>TCAP</i> gene expression in both tissues.https://www.mdpi.com/2076-2615/9/8/574TCAPmuscleArabian horsesgene expressiontraining exercise |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik |
spellingShingle |
Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses Animals TCAP muscle Arabian horses gene expression training exercise |
author_facet |
Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik |
author_sort |
Monika Stefaniuk-Szmukier |
title |
The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses |
title_short |
The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses |
title_full |
The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses |
title_fullStr |
The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses |
title_full_unstemmed |
The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses |
title_sort |
blood and muscle expression pattern of the equine <i>tcap</i> gene during the race track training of arabian horses |
publisher |
MDPI AG |
series |
Animals |
issn |
2076-2615 |
publishDate |
2019-08-01 |
description |
Horse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle’s cross-sectional area under the influence of contractile forces. The aim of the present study was the evaluation of transcript abundance of the telethonin (<i>TCAP</i>) gene, which is a part of the sarcomere macromolecular mechanosensory complex in the gluteus medius muscle, and the whole blood of Arabian horses during flat race training. The analysis, performed by quantitative PCR, showed an increase of <i>TCAP</i> transcripts in skeletal muscle. However, in whole blood, the transcript abundance decreased after the first stage of training and further increased after the second phase. The obtained results indicate a lack of similarity of <i>TCAP</i> gene expression in both tissues. |
topic |
TCAP muscle Arabian horses gene expression training exercise |
url |
https://www.mdpi.com/2076-2615/9/8/574 |
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