The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses

Horse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle...

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Main Authors:	Monika Stefaniuk-Szmukier, Tomasz Szmatoła, Joanna Łątka, Bogusława Długosz, Katarzyna Ropka-Molik
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Animals
Subjects:	TCAP muscle Arabian horses gene expression training exercise
Online Access:	https://www.mdpi.com/2076-2615/9/8/574

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spelling	doaj-bb5fe35c90b44ebf80e42c394a13efd92020-11-25T02:20:26ZengMDPI AGAnimals2076-26152019-08-019857410.3390/ani9080574ani9080574The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian HorsesMonika Stefaniuk-Szmukier0Tomasz Szmatoła1Joanna Łątka2Bogusława Długosz3Katarzyna Ropka-Molik4Department of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, PolandDepartment of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animals Reproduction, Anatomy and Genomics, the University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-159 Kraków, PolandDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, PolandHorse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle’s cross-sectional area under the influence of contractile forces. The aim of the present study was the evaluation of transcript abundance of the telethonin (<i>TCAP</i>) gene, which is a part of the sarcomere macromolecular mechanosensory complex in the gluteus medius muscle, and the whole blood of Arabian horses during flat race training. The analysis, performed by quantitative PCR, showed an increase of <i>TCAP</i> transcripts in skeletal muscle. However, in whole blood, the transcript abundance decreased after the first stage of training and further increased after the second phase. The obtained results indicate a lack of similarity of <i>TCAP</i> gene expression in both tissues.https://www.mdpi.com/2076-2615/9/8/574TCAPmuscleArabian horsesgene expressiontraining exercise
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik
spellingShingle	Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses Animals TCAP muscle Arabian horses gene expression training exercise
author_facet	Monika Stefaniuk-Szmukier Tomasz Szmatoła Joanna Łątka Bogusława Długosz Katarzyna Ropka-Molik
author_sort	Monika Stefaniuk-Szmukier
title	The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
title_short	The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
title_full	The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
title_fullStr	The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
title_full_unstemmed	The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses
title_sort	blood and muscle expression pattern of the equine <i>tcap</i> gene during the race track training of arabian horses
publisher	MDPI AG
series	Animals
issn	2076-2615
publishDate	2019-08-01
description	Horse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle’s cross-sectional area under the influence of contractile forces. The aim of the present study was the evaluation of transcript abundance of the telethonin (<i>TCAP</i>) gene, which is a part of the sarcomere macromolecular mechanosensory complex in the gluteus medius muscle, and the whole blood of Arabian horses during flat race training. The analysis, performed by quantitative PCR, showed an increase of <i>TCAP</i> transcripts in skeletal muscle. However, in whole blood, the transcript abundance decreased after the first stage of training and further increased after the second phase. The obtained results indicate a lack of similarity of <i>TCAP</i> gene expression in both tissues.
topic	TCAP muscle Arabian horses gene expression training exercise
url	https://www.mdpi.com/2076-2615/9/8/574
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The Blood and Muscle Expression Pattern of the Equine <i>TCAP</i> Gene during the Race Track Training of Arabian Horses

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