Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells

Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells

Breast cancer tumors display different cellular phenotypes. A growing body of evidence points toward a population of cancer stem cells (CSCs) that is important for metastasis and treatment resistance, although the characteristics of these cells are incomplete. We used mammosphere formation assay and...

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Bibliographic Details
Main Authors: Emma Jonasson, Salim Ghannoum, Emma Persson, Joakim Karlsson, Thomas Kroneis, Erik Larsson, Göran Landberg, Anders Ståhlberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
breast cancer
cancer stem cell
cell proliferation assay
mammosphere assay
single-cell analysis
single-cell RNA sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00500/full

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