CYTPOWER: IMPLEMENTATION OF CYTOTOXIC POWER CONCEPT IN PYTHON
Currently existing methods and parameters are inadequate for representative and quanititative assessment of cytotoxic activity of chemical compounds. Recently, we have introduced a concept of cytotoxic power which provides an effective way to a reasonable estimation and comparative analysis of cytot...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Cifra Publishing House
2018-11-01
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| Series: | Journal of Bioinformatics and Genomics |
| Online Access: | http://journal-biogen.org/article/view/105 |
| Summary: | Currently existing methods and parameters are inadequate for representative and quanititative assessment of cytotoxic activity of chemical compounds. Recently, we have introduced a concept of cytotoxic power which provides an effective way to a reasonable estimation and comparative analysis of cytotoxic activity of chemical agents. The basis of this concept is an integrative parameter that relies on important toxicological principles: dose of compound related to a cell number and exposure-time-response relationship of its activity.
Herein, we propose a proof-of-concept implementation of our concept of cytotoxic power as a package developed in Python programming language. The package is free and available on GitHub repository. |
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| ISSN: | 2530-1381 |