Neuroanatomical changes in Parkinson′s disease in relation to cognition: An update

The pathophysiological changes underlying impairment of cognition in Parkinson′s disease (PD) are complex and not fully understood till date. Hence, understanding the structural changes responsible for cognitive decline in PD is essential for early diagnosis and to offer effective treatment. In this...

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Bibliographic Details
Main Authors: K G Prakash, B M Bannur, Madhavrao D Chavan, K Saniya, Kumar Sai Sailesh, Archana Rajagopalan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2016;volume=7;issue=4;spage=123;epage=126;aulast=Prakash
Description
Summary:The pathophysiological changes underlying impairment of cognition in Parkinson′s disease (PD) are complex and not fully understood till date. Hence, understanding the structural changes responsible for cognitive decline in PD is essential for early diagnosis and to offer effective treatment. In this review, we discuss the neuroanatomical changes in major brain structures responsible for cognition in PD. We have included the key findings of various studies to provide up-to-date information for better understanding of pathophysiology of PD, which will help researchers and clinicians in planning and developing new treatment methods for the benefit of PD patients.
ISSN:2231-4040
0976-2094