Abstract P-12: Structure of RyR1 in Native Membranes

Background: Ryanodine receptor 1 (RyR1) mediates excitation-contraction coupling by releasing Ca2+ from the lumen of sarcoplasmic reticulum (SR) to the cytoplasm of skeletal muscle cells. RyR1 activity regulation is complicated and modulated by numerous molecules, including several regulatory protei...

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Bibliographic Details
Main Authors: Wenbo Chen, Mikhail Kudryashev
Format: Article
Published: International Medical Research and Development Corporation 2019-06-01
Series:International Journal of Biomedicine
Online Access:http://ijbm.org/articles/IJBM_2019_9_S1_P12.pdf