Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs

This case report describes the clinical, histopathological and immunohistochemical findings in two dogs with myelopathy associated with metastasis of follicular-compact thyroid carcinoma. Microscopically, both primary neoplasms were characterized by polygonal cells arranged in follicles (occasionall...

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Bibliographic Details
Main Authors: Camila Tochetto, Fábio Brum Rosa, Rosmarini Passos dos Santos, Alexandre Mazzanti, Rafael Almeida Fighera, Glaucia Denise Kommers
Format: Article
Language:English
Published: Universidade Federal de Santa Maria 2015-08-01
Series:Ciência Rural
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000801487&lng=en&tlng=en
Description
Summary:This case report describes the clinical, histopathological and immunohistochemical findings in two dogs with myelopathy associated with metastasis of follicular-compact thyroid carcinoma. Microscopically, both primary neoplasms were characterized by polygonal cells arranged in follicles (occasionally filled with eosinophilic colloid-like material) or in sheets. The neoplastic cells had a moderately eosinophilic cytoplasm and there was moderate anisokaryosis and anisocytosis. Additionally, the neoplastic cells were positive for thyroglobulin on immunohistochemistry, confirming the follicular origin of both tumors. This is a very uncommon presentation of this pathological condition.
ISSN:1678-4596