Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs

• Main Authors: Camila Tochetto, Fábio Brum Rosa, Rosmarini Passos dos Santos, Alexandre Mazzanti, Rafael Almeida Fighera, Glaucia Denise Kommers
• Format: Article
• Language: English
• Published: Universidade Federal de Santa Maria 2015-08-01
• Series: Ciência Rural
• Subjects: imuno-histoquímica; oncologia; tumor de tireoide; neurooncologia.
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000801487&lng=en&tlng=en

This case report describes the clinical, histopathological and immunohistochemical findings in two dogs with myelopathy associated with metastasis of follicular-compact thyroid carcinoma. Microscopically, both primary neoplasms were characterized by polygonal cells arranged in follicles (occasionally filled with eosinophilic colloid-like material) or in sheets. The neoplastic cells had a moderately eosinophilic cytoplasm and there was moderate anisokaryosis and anisocytosis. Additionally, the neoplastic cells were positive for thyroglobulin on immunohistochemistry, confirming the follicular origin of both tumors. This is a very uncommon presentation of this pathological condition.